Fachbeiträge Online 
"Sommerekzem der Pferde: Spezifische Immunotherapie (SIT)"
VETimpulse, 11. Jahrgang, Ausgabe 21, 1. November 2002
(Birgit Hunsinger)
"Spezifische Immuntherapie (SIT) beim Hund"
Einfluss von Tieralter, Art und Anzahl der Allergene
Kleintierpraxis, 47. Jahrgang, Heft 8 (August 2002) S. 483-487
(Gudrun Heil-Franke, Birgit HUNSINGER)
Title: "Specific immunotherapy in the dog: influence of age, species and number of allergens"
Abstract: This retrospective study shows the success in hyposensitization of 259 dogs, with
respect to age, species and number of allergens in a solution. The results indicate an optimal
age of 1-8 years for hyposensitization of dogs. A treatment of older dogs can be also
successful but bears more risks. Dogs under 1 year are not recommended for immuno-
therapy. Using only one species of allergen was especially successful. Concerning the
number of allergens in a hyposensitization solution, best efficacy was demonstrated for
up to 6 allergens.
"Diagnose von Haemobartonella felis - Infektionen der Katze"
Kleintierpraxis 47.Jahrgang, Heft 6 (Juni 2002) S. 341-345
(Janine HUEBNER, Petra KÜHNLEIN und Elisabeth MÜLLER)
Title: “Diagnosis of Hemobartonella felis infections in cats" Language: German
Abstract: Haemobartonella-infections in cats are a world-wide problem and with new
diagnostic methods, like polymerase chain reaction (PCR), it becomes clear that a high
percentage of the cat population is infected. Not all of these cats show anaemia and they
appear clinically healthy. These non-anaemic carriers can be a risk factor in breeding and in
transfusion medicine. A comparison of anaemic (n = 69) and non-anaemic (n = 100) animals
shows all together 21,9 % positive cats. But only 54,3 % of all PCR positive samples were
positive by microscopic examination. This shows the advantage of the new more sensitive
method. Interestingly 22 % of the non-anaemic cat group showed positive results as well.
This first study in Germany confirms previous studies in the United Kingdom and the USA.
"Immunvermittelte Hämolytische Anämien (IMHA) bei der Katze"
veterinär spiegel 3/2002, S. 146-150
(Janine HUEBNER)
"Babesiose - Infektionen bei Hund und Katze"
veterinär spiegel 2/2002 ISSN 0940-8711, S. 86-87
(Janine HUEBNER)
"Die Diagnostik der PRRSV-Infektion bei Spätaborten und der Geburt lebensschw. Ferkel"
Tierärztl. Prax. 2002; 30 (G): 324-8; Schattauer GmbH, S. 58-61
(Elisabeth große Beilage, K.Dammann-Tamke, Petra Kühnlein )
Title: “Diagnosing infections of PRRSV in cases of late-abortion and weak-born piglets"
Abstract: The paper reports about a case of clinical disease in a sow herd with late-
abortions, stillbirth and weak-born piglets. The attemptto detect viral or bacterial causative
agents failed. Since the clinical signs pointed to an acute PRRS outbreak, the search for
PRRS antigen was intensified. Thus, the PRRSV infection could be confirmed by the detection
of PRRS antigen by means of PCR in samples from weak-born piglets and sows.
The incidence of transplacental transmission of PRRSV depends on the State of gestation,
with an enhanced likelihood during late gestation. Since typically only some of the fetuses
are infected, appropriate sample sizes (30-50% of the litter) are required. Diagnosis of a
perinatal PRRSV infection can be achieved by PCR using serum samples or lung tissue from
weak-born piglets. Tissue samples must be refrigerated orfrozen soon after collection.
PRRSV could not be isolated from mummified or autolyzed fetuses and frequently could not
be demonstrated from stillborn piglets. The PCR has proven to be a highly sensitive and
specific test for the detection of PRRSV genome. The detection of antibodies against PRRSV
in presuckle serum from weak-born piglets will be uncertain because antibodies are present
only in a minority of infected fetuses. The Interpretation of serum antibodies in sows will be
difficult due to the unknown point of infection.
2001
"Feline ulzerative Dermatitis bei einem Persekater"
Tierärztliche Praxis 29 (K)9: S. 308-11 (2001) Schattauer GmbH
(Ingrid Geyer, Christa Brandenburg, G. Loesenbeck)
Title: "Feline uicerative dermatitis in a Persian cat. A case report" Language: German
Abstract: In this case report the diagnosis, clinical development and therapy of a
"feline uicerative dermatitis" in a male persian cat are described. At the beginning a dramatic
progression and poor response to therapy of an uicerative lesion in the neck was observed.
After three months a complete remission was seen. The possible pathogenesis of this
idiopathic skin disease is discussed.
"Die Bedeutung der Polymerase-Kettenreation (PCR) für die Diagnostik
der Felinen Infektiösen Peritonitis (FIP)"
Kleintierpraxis 46. Jahrgang, Heft 10 (2001) S. 629-634
(Gudrun HEIL-FRANKE, Ludwig HAAS, Marian c. HORZINEK, Elisabeth MÜLLER und
Katja LIESSMANN)
"Seroprävalenz von Antikörpern gegen Neospora caninum bei Hunden mit und ohne
klinischem Neosporoseverdacht in Deutschland"
Der praktische Tierarzt 82: 6, (2001) S.437-440
(Babette Ursula Klein, Elisabeth Müller )
Title: "Seroprevalence of antibodies to Neospora caninum in dogs with and without clinical
suspicion for neosporosis in Germany" Language: German
Abstract: A total of 200 dogs with clinical suspicion for neosporosis mentioned by the
practitioner were tested for the presence of antibodies to Neospora caninum using the indirect
immuno fluorescent antibody test. 87 of these were additionally tested for antibodies to
Toxoplasma gondii. In addition we tested sera from 50 dogs without clinical suspicion for
neosporosis, for antibodies to Neospora caninum. 4 per cent of these were seropositive
(titre > 1:50). Thus a subclinical prevalence in Germany can be assumed. 13 per cent of the
dogs with clinical signs reacted seropositive (titre > 1:50), a clearly higher percentage than in
the group of subclinically infected dogs. Neosporosis should be considered in Germany as a
differential diagnosis in case of respective symptomatology. A simultaneous assessment of
Toxo-plasma-antibodies makes sense because of the similarities of clinical signs between
the belonging diseases. In our study 29 per cent of the sera which were examined
simultaneously were seropositive for Toxoplasma gondii (titre > 1:32) and 11 per cent for
Neospora caninum. Among these only one dog showed a titre against both parasites.
We found a statistically significant higher number of seropositives in the group of male dogs.
This dependence from sex was found for the first time in such a seroprevalence-study for
neosporosis. It requires further investigations in carry-on studies.
2000
"Allergisch bedingte Konjunktivitis bei der Katze"
Kleintierpraxis 45,Heft 12(2000) S.889-956
(Ulrike Blocher,Birgit Hofmann, Gereon Viefhues , Elisabeth Müller)
"Allergien beim Pferd, Spezifische Immuntherapie (SIT) - Hyposensibilisierung"
Pferde Spiegel 4/2000 Seite 11-13
(Beatrice Oldenburg-Ficht)
"DNA-Analysen zur Klärung der Abstammung und Identität / Vaterschaft." (Eurasier)
Kleintiermedizin 4/2000; S.178-180
(P.Kühnlein, E. Müller)
"Kutanes, nicht epitheliotropes T-Zell-Lymphom bei einer Hauskatze"
Kleintierpraxis 45, Heft 8 (2000) S. 629-633
(Ulrike RUNGE-HARMS und Gerhard LOESENBECK)
Title: "Cutaneous, non-epitheliotropic T-cell-lymphoma in a domestic cat"
Abstract: A one-year-old spayed-female domestic shorthair cat was presented with a diffuse
swelling of the right hind limb. Symptomatic treatment remained unsuccessful.
Further examinations and post mortem examinations led to the diagnosis of a T-cell-
lymphoma. The clinical, laboratory, pathological, cytological, histological and immune-
histological changes are described.
"Therapieerfolg bei der Hyposensibilisierung atopischer Hunde."
Kleintiermedizin 45. Jahrgang, Heft 5 (2000) S. 223-225 ( B. Hofmann )
"Indikation serologischer Allergietests bei Hunden."
Der praktischer Tierarzt 81 :8, (2000) S. 622-624 ( G. Loesenbeck )
Title: "Indication of serologic allergy tests in dogs"
Abstract: Modern ELISAs lead to good results as far as the determination of relevant
antigens in atopy and the resulting aqueous hyposenzitation protocol is concerned.
The success rate of hyposenzitation due to the results of ELISAs seems to exceed
70 per cent. Key words: ELISA, allergy, intradermal allergy test, hyposenzitation,
monoclonal antibodies, dog.
